Para-aminobenzoic Acid (PABA)

Type of Drug:

Accessory food factor naturally associated with B-complex vitamins.

How the Drug Works:

A component of several important biochemical processes, PABA and KPAB, working by undefined mechanisms, may prevent or reduce inappropriate fibrosis (making of fibrous tissue). It has no nutrient value. It is not a true vitamin.

Uses:

KPAB only - To treat scleroderma, dermatologists, morphea, linear scleroderma, pemphigus, and Peyronie disease.

Precautions:

Do not use in the following situations: allergy to PABA or KPAB sulfonamide anti-infective therapy, concurrent Use with caution in the following situations: appetite loss nausea kidney disease or impairment

Pregnancy: Adequate studies have not been done in pregnant women. on only if clearly needed and potential benefits outweigh the possible hard's to the fetus.

Breastfeeding: It is not known if PABA appears in breast milk. Consult you" doctor before you begin breastfeeding.

Drug Interactions:

Tell your doctor or pharmacist if you are taking or if you are planning 1o take any over-the-counter or prescription medications or dietary supplements with PABA or KPAB. Doses of one or both drugs may should to be modified or a different drug may need to be prescribed. the following drugs and drug classes interact with PABA or KPAB. dapsonesulfonamides (eg, sulfisoxazole)

Doses:

Side Effects:

Every drug is capable of producing side effects. Many PABA or KPAB users xperience no, or minor, side effects. The frequency and severity of side effects depend on many factors including dose, duration of therapy, and Individual susceptibility. Possible side effects include:

Digestive Tract: Loss of appetite; nausea; vomiting; stomach upset.

Other: Fever; itching; rash; decreased white blood cell count; liver toxicity.

Guldelines for Use:

• Average adult daily dosage is 12 g, given in 4 to 6 separate doses. Six (6) tablets or capsules can be given 4 times daily, usually with meals at bedtime with a snack. Tablets, capsules, and powder (envules) must be taken with an adequate amount of liquid or food to prevent upset. Envules contain 2 g of potassium para-aminobenzoate powder each. Six (6) envies are given for a total of 12 g daily.

• Take with food to minimize stomach upset.

• If s dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose order to catch up, unless advised to do so by your doctor. If more one dose is missed, or it is necessary to establish a new dosage double, contact your doctor or pharmacist.

• If loss of appetite or nausea occurs, stop therapy until you are eating family again.

• Although not a vitamin, this food factor is found naturally associated will B-complex vitamins. Small amounts are found in cereal, eggs, milk and meats.